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NEUROTOLOGICAL STUDIES IN CEREBELLOPONTINE ANGLE TUMORS IN RELATION TO THE MECHANISM OF BRUNS NYSTAGMUS Yasuhiro Chiba 1 , Kazuhiko Fujitsu 1 , Toshinori Yamashita 1 , Hideo Fujino 1 , Takeo Kuwabara 1 , Souji Izumi 2 , Hiroya Yamaguchi 3 , Yutaka Yoshimoto 3 1Department of Neurosurgery, Yokohama City University 2Department of Otorhinolaryngology, Yokohama City University 3Department of Otorhinolaryngology, Toranomon Hospital pp.399-406
Published Date 1977/4/1
DOI https://doi.org/10.11477/mf.1406204053

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  • Abstract
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Recent advances in neurotological studies made possible to determine the site of lesion either from peripheral vestibular, brain stem, cerebellar or cerebral region by careful examinations of ocular movements.

Authors investigated the pattern of nystagmus in fifteen cerebellopontine angle tumors (CPA tumors) and acute stage of six peripheral vestibular or labyrinth lesions during four years (from April 1972 to March 1976). Fifteen CPA tumors included eleven acoustic neurinomas, a trigeminal neurinoma, two meningiomas and an epidermoid tumor. Size of these CPA tumors was that of walnut or bigger.

The neurotological studies in most of fifteen CPA tumors also revealed the finding of brain stem lesions. Thirteen out of fifteen patients with CPA tumor were demonstrated Bruns nystagmus during lateral gaze: Bruns nystagmus was a coarse slow nystagmus and was elicited when a patient looked toward the site of lesion and a more fine rapid nystagmus when looked toward the opposite side. Three out of thirteen patients with CPA tumors (23.1%) demonstrated reversed Bruns nystagmus, which was a coarse slow nystagmus looking toward the opposite side and a more fine rapid nystagmus looking toward the side of lesion.

The developmental mechanism of Bruns nystag-mus was explained by the balance, shown in figures, which was controlled by two kinds of action. One was the action of vestibular organ. The other was the action of the central parts of the oculomotor system containing of paramedian pontine reticular formation (PPRF). PPRF was seemed to have an important role of the development of Bruns nystag-mus.


Copyright © 1977, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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