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THYROID FUNCTION IN MYASTHENIA GRAVIS IN CHILDHOOD Akihisa Mitsudome 1,2 , Nagahide Goya 1,2 , Toru Kurokawa 1,2 , Noriaki Watanabe 1,2 , Satoshi Kono 1,2 1Department of Pediatrics, Faculty of Medicine, Kyushu University pp.529-533
Published Date 1975/5/1
DOI https://doi.org/10.11477/mf.1406203712

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  • Abstract
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Thyroid function was studied in 54 cases withmyasthenia gravis in children and 43 persons oftheir parents and siblings.

Goiter was found in 5 (9%) of 54 cases withmyasthenia gravis.

Two cases had hyperthyroidism, and one of themturned to have hypothyroidism after the treatmentfor hyperthyroidism.

PBI level in serum was more than 8.0 μg/dl in8 cases (32%), and less than 3.5 μg/dl in one case.

Res-O-Mat T3 was abnormally high with morethan 1.1 in 3 cases (14%), and abnormally lowwith less than 0.85 in one case. Res-O-Mat T4was more than 14.0 μg/dl in three cases (14%), andless than 4.0 μg/dl in other 3 cases.

Positive thyroid test was noted in 10% of 28patients, and microsome test was positive in 15%of 26 patients.

Nine patients in our series were noticed to havegoiter or abnormal thyroid functions.

In the 6 family members of 51 families thyroiddisorders were noticed. And thyroid test was posi-tive in 20%, and positive microsome test wasnoticed in 40% of 25 mothers of the patients. Butin none of their fathers and siblings thyroid testor microsome test was positive.


Copyright © 1975, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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