下部消化管にアミロイド沈着を認めた潰瘍性腸病変の1例

Primary Amyloidosis of the Bowel, Report of a Case

　消化管原発アミロイドージスは比較的稀な疾患で，生前診断はつきにくい場合が多いといわれていたが，近年，生検法の発達により生前診断の報告例もふえてきた¹⁾．われわれは小腸および大腸に多彩な潰瘍性病変を有し，直腸，S状結腸の生検でアミロイドの沈着を認めた1例を経験したので報告する．

　We report a case with amyioid deposition in the bowel simulating Crohn's disease. This 42 year-old woman was admitted, complaining of watery diarrhea and episodes of aphthous stomatitis for a year. Radiographic studies revealed multiple areas of ulcera tion, evidence of subrnucosal edema, and narrow segments in the ileum and rectosigmoid, simulating Crohn's disease. Biopsies from the rectosigmoid demonstrated perivascular amyloid deposition in the submucosal layer around an ulcer, but no evidence of Crohn's disease was seen. The patient was kept on hyperalimentation. and recovered. There has been no clinical evidence of systemic amyloid deposition.