Volume 29, Issue 1 (December 2018)
Japanese

The effects of pregnancy and lactation on bone and mineral metabolism. Terauchi Masakazu 1 1Department of Women's Health, Tokyo Medical and Dental University, Tokyo, Japan. pp.35-38
Published Date 2018/12/28
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 To meet the fetus's calcium demand in the 3rd trimester as much as 300~500 mg/day, intestinal calcium absorption in pregnant women is upregulated, without comparable increase in bone resorption. On the contrary, to provide 210 mg/day of calcium for the neonate, bone resorption by osteoclasts and osteocytes is markedly upregulated in maternal skeleton caused by low estrogen and high PTHrP as a consequence of elevated prolactin production, without any increase in intestinal calcium absorption. Breastfeeding women lose 5~10%of trabecular bone during 3 to 6 months of lactation.



基本情報

09175857.29.1.jpg
CLINICAL CALCIUM
29巻1号 (2018年12月)
電子版ISSN 印刷版ISSN 0917-5857 医薬ジャーナル社

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