Volume 27, Issue 4 (March 2017)
Japanese

Update on drugs acting on calcium-sensing receptor. The functions of calcium-sensing receptor in regulating mineral metabolism. Kinoshita Yuka 1 1The functions of calcium-sensing receptor in regulating mineral metabolism. pp.491-497
Published Date 2017/3/24
DOI https://doi.org/10.20837/4201704021
  • Abstract
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 Calcium-sensing receptor(CaSR)which belongs to a G protein-coupled receptor family is one of the key elements in regulating calcium homeostasis. CaSR has been identified as a receptor to control parathyroid hormone(PTH)secretion in parathyroid glands according to serum calcium ion(Ca2+)levels. It has also been shown that CaSR controls reabsorption of water and several cations including Ca2+and magnesium ion(Mg2+)in renal tubular cells. This review summarizes the functions and roles of CaSR in mineral metabolism that are exerted in parathyroid glands, kidney, and intestine.



基本情報

09175857.27.4.jpg
CLINICAL CALCIUM
27巻4号 (2017年3月)
電子版ISSN 印刷版ISSN 0917-5857 医薬ジャーナル社

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