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Zinc signaling-mediated regulation of dentin and periodontal tissues. Fukada Toshiyuki 1 , Idaira Yayoi 2 , Shimoda Shinji 3 , Asada Yoshinobu 4 1Tokushima Bunri University, Faculty of Pharmaceutical Sciences, Molecular and Cellular Physiology, Japan. 2Department of Pediatric Dentistry, Tsurumi University, School of Dental Medicine, Japan. 3Department of Oral Anatomy, Tsurumi University, School of Dental Medicine, Japan. 4Department of Pediatric Dentistry, Tsurumi University, School of Dental Medicine, Japan. pp.1862-1871
Published Date 2015/11/28
DOI https://doi.org/10.20837/4201512122
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 An essential trace element zinc is required for variety of cellular functions and physiological responses, therefore, downregulation of zinc homeostasis cause serious problems in health, such as growth retardation and abnormal bone formation. Recent technical advances contributed to reveal that zinc ion regulated by zinc transporters acts as a signaling mediator, called zinc signaling that involves in mammalian physiology and pathogenesis. This review will address the current understanding of the roles of zinc signaling in regulation of dentin formation and periodontal tissues homeostasis.



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電子版ISSN 印刷版ISSN 0917-5857 医薬ジャーナル社

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