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The Japanese Journal of Thoracic Surgery Volume 75, Issue 5 （May 2022）

胸部外科 75巻5号（2022年5月発行）

Japanese English

臨床経験

肺性肥大性骨関節症合併肺癌に対する外科治療 Surgical Treatment for Lung Cancer Associated with Hypertrophic Pulmonary Osteoarthropathy 藤田朋宏 ¹ , 小林数真 ¹ , 江場俊介 ¹ , 佐藤伸之 ¹ Tomohiro Fujita ¹ , Kazuma Kobayashi ¹ , Shunsuke Eba ¹ , Nobuyuki Satou ¹ ¹青森県立中央病院呼吸器外科 ¹Department of Thoracic Surgery, Aomori Prefectural Central Hospital キーワード：肺癌 , 肺性肥大性骨関節症 , 外科治療 Keyword: lung cancer , hypertrophic pulmonary osteoarthropathy , surgical treatment pp.363-367

発行日 2022年5月1日 Published Date 2022/5/1

DOI https://doi.org/10.15106/j_kyobu75_363

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肺性肥大性骨関節症（hypertrophic pulmonary osteoarthropathy：HPO）はばち状指，長管骨の骨膜新生，関節炎を特徴とする腫瘍随伴症候群の一つである1）．関節痛，関節腫脹，関節可動域の制限により日常生活動作（ADL）の著しい低下をきたす．われわれは，HPO合併非小細胞肺癌に対して外科治療を行い，関節症状の劇的な改善を認めた2例を経験したので報告する．

Hypertrophic pulmonary osteoarthropathy （HPO） is a rare paraneoplastic manifestation of lung cancer that causes joint pain, joint swelling, and limited range of motion. Two surgical cases of lung cancer with HPO are presented.

Case1：A 43-year-old female was referred to our department with a diagnosis of cStage ⅡB left hilar lung cancer. She had difficulty in walking due to arthralgia caused by HPO. Left pneumonectomy was performed and the arthralgia disappeared on the first postoperative day. The patient is being well after surgery without relapse of joint symptoms.

Case2：The patient was a 65-year-old male with cStage ⅡA right lung cancer. The symptoms of HPO appeared after he was found to have lung cancer. After right upper lobectomy, the arthralgia disappeared on the first postoperative day. Currently, he is receiving adjuvant chemotherapy, without relapse of joint symptoms.