原発性多発肺髄膜腫

Multiple Primary Pulmonary Meningiomas

髄膜腫は中枢神経系の腫瘍で，硬膜から発生し髄膜皮細胞によって構成されている．一般に発育は緩徐で，予後は良好なものが多い．原発性脳腫瘍としては比較的頻度の高いものであるが，中枢神経系以外に発生する異所性のものはまれで，なかでも原発性肺髄膜腫はきわめてまれである．われわれは，卵巣未熟奇形腫の術後遠隔期に両肺に多発する肺腫瘤に対し手術を行い，多発性原発性肺髄膜腫の診断を得た症例を経験したので報告する．

We report a rare case of multiple primary pulmonary meningiomas in a 52-year-old woman who presented with lung nodules identified on abdominal computed tomography （CT）. She had a history of surgery and chemotherapy for an immature ovarian teratoma 33 years prior to presentation. She underwent resection of a mature retroperitoneal teratoma 16 years prior and a peritoneal teratoma 6 months prior to presentation. Chest CT revealed 3 solid nodules in the right S3, right S8, and left S6 lung segments, and we performed thoracoscopic resection. Histopathologically, the 3 tumors were diagnosed as meningiomas. Since these tumors did not have other histological component and magnetic resonance imaging of the central nervous system revealed no meningeal lesion, these tumors were diagnosed as primary pulmonary meningiomas.