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要旨:局所皮膚麻酔により前腕からの求心路を遮断すると,同側指尖の触知覚が向上するとして知覚再学習に適用されている.一方,メントール剤の局所貼付は鎮痛作用があると報告されている.本研究ではメントール剤の求心路抑制作用とその指の触知覚への影響を検証した.まず,健常者7名の右前腕にメントール剤を貼り,対側同部位と比較したところ,触覚閾値の軽度上昇を認めた.次に健常者38名を2群に分け,それぞれメントール剤・プラセボ剤を右前腕に貼付し同側指尖の触覚閾値,2点識別値の変化を調べた.その結果,メントール剤貼付後は小指の動的2点識別値の減少が認められ,メントール剤の前腕貼付による同側指の触覚識別能の向上が示唆された.
Recently, studies have shown that selective temporary forearm cutaneous anesthesia improved finger tactile perception. Increased cortical hand representation accompanied this finding. Researchers have reported that Menthol applied to the skin caused superficial analgesia. We hypothesized that the application of menthol patches to the forearm will improve the hand's tactile perception. The aim of this study was to investigate the effect of the application of menthol patches to the forearm on hand tactile perception. To accomplish this, we conducted two separate experiments. Experiment one had a group of seven healthy subjects and investigated forearm tactile threshold after the application of menthol patches. The patches application resulted in an increase in forearm tactile threshold. The study indicated that cutaneous anesthesia of the forearm occurred after applying menthol patches. Experiment two was a randomized, controlled study that investigated the tactile perception of the hand in two groups of 19 normal subjects. The experimental group applied a menthol patch to the forearm while the control group received a placebo patch. The results indicate a statistically significant improvement of Moving 2pd in one segment of the experimental hand. However, the study found no statistically significant difference between the two groups in tactile threshold or Static 2pd in any hand segments. The study concludes that application of menthol patches to the forearm results in increased tactile threshold of the forearm and improved Moving 2pd of the hand. These findings suggest that application of topical menthol patches to the forearm will enhance tactile spatial acuity of the finger.
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