修正型電気けいれん療法後の記憶と気分の障害に対する個別作業プログラムの効果

The effect of an individual activity program for memory and mood disorders following modified electroconvulsive therapy

要旨：修正型電気けいれん療法（以下，ECT）を施行した患者に個別の作業プログラムを実施し副作用である記憶障害や気分の障害に及ぼす効果を検討した．ECT施行患者を介入群（13名）と非介入群（13名）にランダムに割り付け，介入群にのみ個別作業プログラムを実施した．1ヵ月後の機能の全体的評定尺度（以下，GAF），Mini-Mental State Examination（以下，MMSE），三宅式記銘力検査，気分と疲労のチェックリスト（以下，SMSF）の変化を比較した．その結果，GAF，MMSE，三宅式記銘力検査で差はなく，SMSFの変化は介入群でより大きかった．個別作業プログラムがECTを受けた患者の気分を安定させる効果をもつことが示唆された．

　An individual activity program was administered to patients in an intervention group who underwent modified electroconvulsive therapy (ECT). This study examined the effect of this program on memory impairment and mood disorders, as well as the common side effects of ECT. Patients who received ECT were randomly assigned to an intervention group (n=13) and a control group (n=13). Scores of the Global Assessment of Functioning (GAF), Mini-mental State Examination (MMSE), Miyake-style retention test, and the Inventory Scale for Mood and Sense of Fatigue (SMSF) were compared before administration of the program and 1 month after initiation of the program in both the intervention and non-intervention groups. Results of the GAF, MMSE, and Miyake-style retention tests were similar in both groups, but significantly larger differences were noted in the results of the SMSF in the intervention group. This study suggests that the individual activity program had a stabilizing effect on patients who received ECT in the intervention group.