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Hepatitis C Virus Antibodies Among Different Groups at Risk and Patients With Suspected Non-A, Non-B Hepatitis pp.68-69
Published Date 1992/1/1
DOI https://doi.org/10.11477/mf.1543900928
  • Abstract

4000 sera were tested for antibodies against hepatitis C virus (HCV) by means of an ELISA using the C100-3 antigen. 38.9% of patients with non-A, non-B hepatitis following blood transfusion (n=108) had HCV antibodies. Among patients with chronic liver damage of unknown origin (n=316) 30.4% were anti-HCV positive, and in 2,506 patients with transitional or chronic elevation of transaminases 14.8% showed HCV antibodies. Haemophiliacs (n=26) with 65.4% anti-HCV positives and drug addicts (n=46) with 56.5 % anti-HCV positives had the highest prevalence among high risk groups. Addictsdying from drug abuse (n=216) and HIV 1 positives (n=127) wereanti-HCV positive in 37.5% and 26.0%, respectively. Patients onhaemodialysis (n=331) had antibodies against HCV in 12.4%. Healthcare workers (n=217) appear to be at a comparably low risk withonly 2.8% anti-HCV positives. Up to now we could not find a singlecase of intrafamilial spread of HCV in 46 examined cases. Wesuggest that HCV infectivity of contaminated body fluids and blood islower than that of hepatitis B virus or human immunodeficiency virustype 1 carriers.


Copyright © 1992, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1375 印刷版ISSN 0301-2611 医学書院

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