雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

検索

書誌情報 詳細検索 by 医中誌

Japanese

Vasculitis syndromes Shoichi Ozaki 1 1Division of Rheumatology and Allergology, Department of Internal Medicine, St. Marianna University School of Medicine Keyword: 抗糸球体基底膜抗体 , 抗好中球細胞質抗体 , 抗内皮細胞抗体 pp.1164-1171
Published Date 2011/10/30
DOI https://doi.org/10.11477/mf.1542102798
  • Abstract
  • Look Inside
  • Reference

Vasculitis syndromes primarily aggravate the inflammation of vessel walls. Most of the syndromes are multi-factorial, and the pathogenesis requires the interactions of genetic and environmental factors. Those pathological steps may induce an autoimmune phenomenon, and in turn lead to immunological attack of the vessel walls. Both cellular and humoral immune systems are involved in the pathogenesis : autoreactive T lymphocytes and autoantibody-producing B lymphocytes with specificities for the glomerular basement membrane, neutrophil cytoplasmic antigens or endothelial cell antigens. The breakdown of tolerance to these autoantigens may result in development of some vasculitis syndromes.


Copyright © 2011, Igaku-Shoin Ltd. All rights reserved.

基本情報

電子版ISSN 1882-1367 印刷版ISSN 0485-1420 医学書院

関連文献

もっと見る

文献を共有