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Auditory Brain Stem Respose, Caloric Reaction and Stapedial Reflex in a Comatose Patient due to Intoxication of Netrazepam and Chlorpromazine Taiji Nagai 1 1Department of Otolaryngology, Teikyo University, School of Medicine pp.33-37
Published Date 1982/1/20
DOI https://doi.org/10.11477/mf.1492209383
  • Abstract
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 A 33-year- old woman who failed in committing suiside by taking excessive dose of netrazepam and chlorpromazine was evaluated for her comatose state. The depth of unconsciousness was monitored by auditory brain stem response, caloric reaction, and stapedial reflex. For treatment of her comatose state, direct hemoperfusion (DHP) was performed to remove the toxic substances from her blood.

 On the first hospital day, ABR was normal but both caloric reaction and stapedial reflex were diminished. With repetition of DHP, both caloric reacion and stapedial reflex were improved gradually and finally became normal. These findings suggest that stapedial reflex and caloric reaction are useful indicators of the brain stem function in comatose patients due to sedative intoxication.

 After DHP twice, she recovered from comatose state and was discharged on the third hospital day.


Copyright © 1982, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 印刷版ISSN 0386-9679 医学書院

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