耳漏中の細菌とその薬剤感受性

MICROBES IN THE OTORRHOEA AND THEIR SENSITIVITY TO ANTIBIOTICS

　Ⅰ．緒言

　最近の抗生物質製法の著しい進歩によつて多数の新しい抗生物質が登場してきた。一方，中耳炎の手術件数が減少し，外来で抗生物質を使用しながら治療する機会が増加した。この際問題となるのは当然のこととして起炎菌の種類とその薬剤感受性についてであるが，氾濫ともいえる抗生物質の増加と薬剤耐性菌の出現によつてfirst choiceとしてどの薬剤を使用するのが良いか，通りいつぺんの判断が通用しなくなつてきた傾向にある。そこで最近の中耳炎における菌の動態とその薬剤感受性を調べた結果が以下に報告する主な内容である。

　A study was conducted to investigate the types of bacterial growth that may be found in the aural discharges of the acute, and chronic otitis media and from operated cases. In acute otitis media staphylococci were found in most cases, but in chronic otitis and in operated cases, pseudomonas, proteus and enterobacteriaceae with staphylococci, either in combination or independently.

　The acute otitis media is mostly caused by invasion of singular type of bacteria but in chronic otitis and in the operated cases mixed infection was usually the case.

　Staphylococci in acute otitis media are usually highly sensitive to many antibiotics. Staphylococci obtained from chronic otitis and operated cases were much less sensitive to any form of antibiotics. This sensitivity appeared to be almost negative in cases of pseudomonas infection.