犬尿管筋電図に及ぼす自律神経剤の影響—第3報 尿管筋電図に於ける自律神経剤の拮抗関係

THE EFFECT OF SYMPATHETIC AND PARASYMPATHETIC DRUGS ON THE ELECTRO MYOGRAMS OF THE DOG'S URETER : 3. ANTAGONISTIC ACTION OF SYMPATHETIC AND PARASYMPATHETIC DRUGS ON THE ELECTROURETEROGRAM

　第1報，第2報に引き続き，犬尿管筋電図に於て波数の増加の著明であつた副交感神経興奮剤アセチルコリンに対して副交感神経麻痺剤であり，波数の減少の著明であつたブスコパン，及び減少の明らかでなかつたアトロピン，また交感神経剤についても同様に波数の増加の著明であつた興奮剤アドレナリンに対して交感神経麻痺剤として波数の著明な減少を示したイミダリン，波数の減少の著明でなかつたエルゴタミンを選び，それぞれ混合静注した場合の犬尿管筋電図を摘記観察し，これら薬剤相互の拮抗関係について2，3の知見を得た。

The exposed ureters of 32 adult dogs were examined electromyographically under mixed intravenous administration of parasy mpatho-mimetic drugs acetylcholine, parasympatho-lytic drugs buscopane, atropine and sympatho-mimetic drugs adrenaline, sympatholytic drugs imidaline and ergotamine.

Injecting acetylcholine and adrenaline se-parately, the electroureterogram was taken asa control and the antagonistic relations be-tween these were observed.

1) After administration of the usual dosis of acetylcholine alone, the electroureterogram showed a marked in wave frequency and prolonged propagation velocity.