Neurological Surgery No Shinkei Geka Volume 28, Issue 1 (January 2000)

A Successfully Operated Case of Choriocarcinoma with Recurrent Intratumoral Hemorrhage Kaori SAKURADA 1 , Takamasa KAYAMA 1 , Keita KAWAKAMI 1 , Makoto SAINO 1 , Shinya SATO 1 1Department of Neurosurgery, Yamagata University School of Medicine Keyword: biopsy , chemotherapy , choriocarcinoma , intratumoral hemorrhage , radical resection pp.67-72
Published Date 2000/1/10
  • Abstract
  • Look Inside

A 12-year-old boy with primary intracranial choriocarcinoma of the pineal region suffered from repeatedintratumoral hemorrhage over a short period. Neuroradiological images demonstrated a pineal-regiontumor with intratumoral hemorrhage and obstructive hydrocephalus. HCG-β subunit concentration of hisserum and cerebrospinal fluid was abnormally high. After the 24.2Gy irradiation, the tumor was removedalmost totally. After the operation, we treated him with additional radiation and chemotherapy using ifos-famide, cisplatin, and etoposide (namely ICE therapy).

No recurrence or metastasis has been noted, and be was in good condition during the 22 months sincethe operation. At present he receives maintenance ICE therapy every 3 months. Choriocarcinoma involvesa high possibility of intratumoral fatal hemorrhage, so a radical operation is recommended as soon aspossible.

Copyright © 2000, Igaku-Shoin Ltd. All rights reserved.


Neurological Surgery 脳神経外科
28巻1号 (2000年1月)
電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院