頭蓋骨に発生した線維性黄色腫の1例

A Case of Xanthofibroma of the Skull

I．はじめに

　黄色腫は，一般に高脂血症や糖尿病などの代謝異常症に合併し，皮膚や軟部組織に発生する疾患で，骨原発のものは稀であり，とりわけ頭蓋骨に発生したものの報告はきわめて少ない．われわれが経験したxanthofibromaに関し，若干の文献的考察を加え報告する．

The authors describe a case of xanthofibroma of the skull. A 53-year-old female was admitted to our hospital in September, 1991, with subarachnoid hemorrhage dueto a ruptured aneurysm of the anterior communicating artery. The roentogenogram of her skull incidentally rev-ealed the presence of a radiolucent (a punched out) le-sion of about 20×25mm in the right occipital bone.

On computed tomography (CT), the mass was seen to be mainly localized in the diploe, and the outer table of the skull was thinned. On both T1 and T2 weighted magnetic resonance image (MRI), the mass showed a high intensity signal equivalent to that found in adipose tissue.

The bony tumor was totally removed. Histology re-vealed a collection of foamy cells, benign fibrous tissues and so on which led to a diagnosis of xanthofibroma of the skull without hyperlipidemia.

Xanthofibroma of the skull is extremely rare. To our knowledge, including our case, only three cases have been reported.