偽膜性大腸炎の臨床的検討—脳神経外科の立場から

Clinical Study of Pseudomembranous Colitis: A neurosurgical viewpoint

I．はじめに

　偽膜性大腸炎は抗生物質投与によってClostridiumdifficile（以下，C．difficile）の異常増殖がおこり，大腸に散在性の偽膜形成を伴う炎症性疾患である^1,9）．脳神経外科領域においても抗生物質を投与する機会が多く，本症に遭遇する危険性がある．

　過去3年間で6例の偽膜性大腸炎併発例を経験し，とくに主症状である下痢に注目し，脳神経外科の立場で臨床的検討を行ったので報告する．

In many instances patients who have undergone neurosurgery are given antibiotics. Some of these patients, however, run the risk of developing pseudomembranous colitis.

In our department over the past three years, 239 patients, whose hospitalization period exceeded two weeks, were given antibiotics. Of this total number, 6 patients (2.5%) contacted pseudomembranous colitis and a clinical study of these 6 cases was conducted from a neurosurgical viewpoint.