Frequently Recurring Cerebral Amyloid Angiopathy-related Hemorrhages within a Short Period of Time:A Case Report Yusuke EBIKO 1 , Shogo IMAE 1 1Department of Neurosurgery, Fujiyoshida Municipal Medical Center Keyword: cerebral amyloid angiopathy , cerebral amyloid angiopathy-related inflammation , multiple cerebral hemorrhage pp.827-833
Published Date 2020/9/10
DOI https://doi.org/10.11477/mf.1436204279
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 We encountered a case of cerebral amyloid angiopathy(CAA)-related cerebral hemorrhage that recurred 20 times within 9 months. The patient was a 68-year-old woman with a history of hypertension, and whose blood pressure was controlled with antihypertensive medicine. She was hospitalized due to cerebral hemorrhage of the right temporal lobe and underwent conservative treatment;however, cerebral hemorrhage of the right frontal lobe recurred on day 60, and 18 cerebral hemorrhages occurred in the following 7 months. Most of the bleeding occurred in the cerebral subcortex, and CAA-related inflammation(CAA-I)had appeared to have developed since subacute progressive cerebral white matter lesions and meningeal contrasting findings were found with MRI. Although cerebral hemorrhage recurrence was not observed for 1 month after steroid pulse therapy, cerebral hemorrhage was subsequently repeated. Thus, in rare cases, CAA-I results in the recurrence of cerebral hemorrhage within a short period of time, and steroids may be effective for preventing this recurrence.

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