AIDS発症に関連した頭蓋内悪性リンパ腫の1手術例

Primary Intracranial Malignant Lymphoma Associated with Acquired Immunodeficiency Syndrome（AIDS）:A Case Report

Ⅰ．はじめに

　本邦では，ヒト免疫不全ウイルス（human immunodeficiency virus：HIV）感染者数は増加していると報告されており，今後，HIV感染者に対して手術を行う機会も増加すると考えられる．頭蓋内悪性リンパ腫は，HIV感染による後天性免疫不全症候群（acquired immunodeficiency syndrome：AIDS）における合併症の中でも特に予後不良で治療は困難を極め，2年死亡率は84%を超えるとの報告もある^1,11)．今回われわれは，AIDSに関連した原発性中枢神経系悪性リンパ腫（primary central nervous system lymphoma：PCNSL）の手術症例を経験したので，医療従事者側の感染を防ぐための術中予防対策を含めて報告する．

　The spread of human immunodeficiency virus（HIV）infection may result in an increased likelihood of surgery in patients with HIV infection. We treated a patient with intracranial malignant lymphoma associated with acquired immunodeficiency syndrome（AIDS）caused by HIV infection. The recommendations of the countermeasure manual for AIDS were followed. Only surgical staff without finger injury or inflammation were permitted to be involved in the operation. All staff were dressed in a waterproof, full-body surgical gown, and wore double gloves, double foot covers, and an N95 mask. The surgery could be performed safely with such infection control measures. Histological examination revealed a diffuse large B-cell lymphoma. The patient was referred to the Division of Infectious Diseases and Respiratory Medicine for chemotherapy.