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Brain Tumor Induced in Dogs by Intracerebral Inoculation of SR-RSV Induced Cultured Tumor Cells: Electron microscopic study Toshiro SHIMURA 1,4 , Asao HIRANO 1 , Kaoru HINOKUMA 2 , Thomas Kaye 2 , Iwao TAKESHITA 3 1Division of Neuropathology, Department of Neuropathology, Montefiore Medical Center, Albert Einstein College of Medicine 2Department of Neurological Surgery, Albert Einstein College of Medicine 3Department of Neurosurgery, Neurological Institute Faculty of Medicine, Kyushu University Keyword: Brain neoplasma , Electron microscopy , Canine model , S-R strain of Rous sarcoma virus , Immunohistochemistry pp.521-528
Published Date 1985/5/10
DOI https://doi.org/10.11477/mf.1436202012
  • Abstract
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An experimental transplantable canine brain tumor model with the advantages of rapid tumor growth within 10 days and relative safety for the investigator is presently available. The tumor is produced by intracerebral inoculation of cultured cells derived from a canine brain tumor induced by the Schmidt-Ruppin strain of the Rous-Sarcoma virus (SR-RSV). It has potential use as a model in experiments designed to evaluate the effectiveness of chemotherapy and radiotherapy with serial computerized tomography scans. However, characterization of the induced tumor is essential.


Copyright © 1985, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院

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