Neurological Surgery No Shinkei Geka Volume 33, Issue 8 (August 2005)

A Case of Giant Cell Tumor in Atlas Hirohito TSUCHIYA 1 , Yasuaki KOKUBO 1 , Kaori SAKURADA 1 , Yukihiko SONODA 1 , Shinjiro SAITO 1 , Takamasa KAYAMA 1 1Department of Neurosurgery,Yamagata University School of Medicine Keyword: giant cell tumor , atlas , surgical removal , radiation , coil embolization pp.817-823
Published Date 2005/8/1
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We report a rare case of giant cell tumor in the atlas. A 50-year-old female presented with severe pain in her right neck and shoulder. The preoperative magnetic resonance images showed a tumor mixed with solid and cystic components in the right side of the atlas. CT scan showed that the anterior and posterior arches of the atlas were destroyed. Preoperative biopsy led to the pathological diagnosis of giant cell tumor with multinuclear giant cells and mononuclear stromal cells. A preoperative vertebral angiogram demonstrated tumor stain supplied from the muscular branches. To reduce intraoperative bleeding,the embolization of the right vertebral artery by GDC was performed before surgical removal. The tumor was subtotally removed following ligation of the right external carotid artery to reduce bleeding of tumor. We used the Olerud cervical system to prevent cervical instability after resection of the tumor. Although the symptoms disappeared completely after surgery,regrowth of tumor was observed in follow-up MRI 4 months after the operation. For this reason,local radiation therapy was performed (50Gy). Then,the size of the tumor has not changed in the 1.5 years since the operation.

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Neurological Surgery 脳神経外科
33巻8号 (2005年8月)
電子版ISSN 1882-1251 印刷版ISSN 0301-2603 医学書院