Experimental Neurofibrillary Change Induced by Aluminum Lactate Hiroo Mori 1 , Haruomi Nakamura 1 , Kiyoshi Wakutani 1 1Division of Neuropathology, Institute of Neurological Sciences, Tottori Univ.School of Med. pp.279-290
Published Date 1969/6/25
DOI https://doi.org/10.11477/mf.1431906446
  • Abstract
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Thirty two rabbits received intracranially 0.05 cc of alminum lactate in satulated solution. At-different intervals after administration, the anim-als were sacrificed for neuropathologic examinations. Electron microscopic observation was performed on three rabbits. The results were as follows.

1) Neurofibrillary change (NFC) was found in 27 of 32 rabbits. The minimum change developed at third day after administration and the most prominent change was observed at 7th to 14th day.

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