The history of headache, the evolution of knowledge. Shinya MANAKA 1 1Department of Neurosurgery, Manaka Hospita Keyword: 頭痛 , 歴史 , 発生機序 , 治療 pp.331-340
Published Date 2002/6/10
DOI https://doi.org/10.11477/mf.1431901357
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The historical epoch of headache research was divided into six era as following ; I . from an ancient period to Hippocrates (“magical” era) II. from Hippocrates to the 17th century (“the four cardinal humors” era) III. form Willis (1660) to Wolff (1940) (renaissance for headache) IV. from 1940 to 1987 (innovation of headache research) V. from 1988 to 2000 (era of triptans) VI. after 2001 (era of molecular biology)

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