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Japanese

Electrophysiological evaluatlon of brain function in impending brain death; Temporal correlation with intracranial circulatory arrest. Toshiyuki SHIOGAI 1 , Kazuo TAKEUCHI 1 1Department of Neurosurgery, Kyorin University School of Medicine pp.296-307
Published Date 1992/4/10
DOI https://doi.org/10.11477/mf.1431900232
  • Abstract
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The aim of this study was to clarify the diagnostic ambiguity caused by discrepancies between electrohysiological loss of neuronal function in the cerebrum and brainstem and intracranial circulatory arrest in impending brain death. One hundred of 203 consecutive patients with severe brain damage were evaluated with a continuous, multimodal neuromonitoring system. The system included somatosensory evoked potentials (SEP) and compressed spectral array (CSA) for the assessment of cerebral cortical function, brainstem auditory evoked potentials (BAEP) and SEP for the evaluation of brainstem neuronal function, and transcranial Doppler sonography (TCD) for the measurement of supratentorial circulation in the middle cerebral artery. Each neuromonitoring modality was conducted serially and assessed every 10-30 minutes. The causes of brain damage were cerebrovascular accident in 52 cases, head injury in 39, brain anoxia in 7, and meningitis in 2. Mean age of the patients was 49 (range, 1-84). Based on CT findings, the cases were classified as supratentorial mass lesions (59 cases), diffuse (32 cases) or infratentorial (9 cases) lesions. Twenty patients who received barbiturate treatment were analyzed separately, as barbiturates may influence CSA findings.


Copyright © 1992, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1243 印刷版ISSN 0001-8724 医学書院

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