Schizophrenia:disturbance of the self and sociality-related circuits Masayoshi Kurachi 1 1Department of Neuropsychiatry, Faculty of Medicine, Toyama University Keyword: 統合失調症 , schizophrenia , 自己の障害 , disturbance of the self , mirror neuron , Sylvius周辺構造 , peri-Sylvian structures pp.142-152
Published Date 2006/2/10
DOI https://doi.org/10.11477/mf.1431100029
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Magnetic resonance imaging studies on schizophrenia patients have revealed significant grey matter volume reduction in the limbic systems(amygdala, hippocampus), paralimbic cortices(insula, cingulated gyrus), superior temporal gyri, and dorsolateral frontal lobes in the left hemisphere predominantly. It should be noted that Peri-Sylvian structures including the speech area and mirror neuron systems are often involved. Clinical symptoms in schizophrenia are characterized by disturbance of the self, and these symptoms may become understandable, if we assume the dysfunctional state of the mirror neuron systems.

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