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Neurobiology of Loneliness, Social Isolation, and Affiliative Social Behavior Kansai Fukumitsu 1 , Kumi O Kuroda 1 1Laboratory for Affiliative Social Behavior, RIKEN Center for Brain Science Keyword: 社会的孤立 , 孤独 , アミリン , カルシトニン受容体 , 内側視索前野 , social isolation , loneliness , amylin , calcitonin receptor , medial preoptic area pp.263-268
Published Date 2023/3/1
DOI https://doi.org/10.11477/mf.1416202318
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Abstract

Prolonged social isolation has been reported to be one of the risk factors for human health, equivalent to smoking cigarettes. Therefore, some developed countries have recognized prolonged social isolation as a social problem and have started to address this problem. Studies on rodent models are essential to fundamentally clarify the impacts of social isolation on human health mentally and physically. In this review, we conduct an overview of the neuromolecular mechanisms of loneliness, perceived social isolation, and the effects of prolonged social isolation. Finally, we consider the evolutionary development of neural bases of loneliness.


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電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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