BRAIN and NERVE Shinkei Kenkyu no Shinpo Volume 70, Issue 7 (July 2018)

Continuous Blood Glucose Monitoring of Hyperglycemia in Acute Stroke Patients Receiving Enteral Tube Feeding Shigen Kasakura 1 , Takahisa Mori 1 , Noriyoshi Nakai 1 , Yuhei Tanno 1 , Kazuhiro Yoshioka 1 1Department of Stroke Treatment, Shonan Kamakura General Hospital Stroke Center Keyword: 持続血糖測定 , 急性期脳卒中 , 高血糖 , 経管栄養 , continuous glucose monitoring , acute stroke , hyperglycemia , enteral tube feeding pp.849-855
Published Date 2018/7/1
  • Abstract
  • Look Inside
  • Reference


Severe hyperglycemia often occurs when acute stroke patients receive enteral tube feeding. Hyperglycemia should be managed because it adversely affects stroke outcome. However, it remains unclear how blood glucose level (BGL) changes with enteral nutrition in acute stroke patients. Our purpose was to investigate features of the blood glucose curve in acute stroke patients receiving enteral feeding. We retrospectively evaluated acute stroke patients who developed hyperglycemia during enteral tube feeding and underwent CGM in our institution. We evaluated characteristics of blood glucose curves, fasting and peak BGL, and time to peak of BGL. Six patients were analyzed. The median fasting BGL was 125.5 mg/dL and the median peak BGL was 351.5 mg/dL. The blood glucose curve showed the following characteristics following: 1) BGL elevated slowly reach the peak in 180 to 240 minutes; 2) BGL decreased slowly or very little after its peak; 3) there was a large gap between fasting and peak BGL regardless of presence of diabetes mellitus. We grouped the curves into four types by time to peak and how BGL decreased after peak.

(Received August 17, 2017; Accepted February 1, 2018; Published July 1, 2018)

Copyright © 2018, Igaku-Shoin Ltd. All rights reserved.


BRAIN and NERVE-神経研究の進歩
70巻7号 (2018年7月)
電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院