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The Neural Mechanisms of Cigarette Craving and Self-control Takuya Hayashi 1 1RIKEN Center for Life Science Technologies (CLST), Functional Architecture Imaging Unit Keyword: 依存症 , 神経画像法 , 経済学 , 意思決定論 , 欲求 , addiction , neuroimaging , economics , decision-making , craving pp.33-39
Published Date 2014/1/1
DOI https://doi.org/10.11477/mf.1416101691
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Abstract

A craving for cigarettes or drugs has been believed to be a fundamental psychopathological factor that drives drug-seeking behavior and relapse. Behavioral economics has revealed context-dependent changes in drug craving. Neuroimaging studies have also found craving-related signals that were altered depending on the context of the experiments. A rational decision-making theory modeled such context-dependency and uncovered a pivotal role of the prefrontal cortical circuit in both self-control and craving. Future studies should address how dopaminergic function and stress circuits can modify the function of decision-making circuits, and produce either craving or self-control.


Copyright © 2014, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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