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Risk Factors for Fractures in Parkinson's Disease: A Questionnaire Survey Kei Fukada 1,2 , Masaru Yokoe 1 , Takanori Hazama 2 , Yoichi Yamamoto 3 , Hideki Mochizuki 1 , Saburo Sakoda 1,4 1Department of Neurology, Osaka University Graduate School of Medicine 2Department of Neurology, Osaka General Medical Center 3Center for Clinical Investigation and Research, Osaka University Hospital 4Toneyama National Hospital Keyword: Parkinson's disease , fracture , risk factor , psychiatric symptom , fall pp.687-692
Published Date 2013/6/1
DOI https://doi.org/10.11477/mf.1416101523
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Abstract

 This study investigated the risk factors for fractures in patients with Parkinson's disease (PD). A questionnaire specifically designed to examine these risk factors was mailed to 172 PD patients registered in our self-developed PD database. We subsequently received replies from 158 patients, 22(14.8%)of whom had experienced fractures after PD onset. A multiple logistic regression model was used to evaluate the responses, and together with the clinical information stored in our PD database, it was revealed that psychiatric symptoms and falls within 1 year of our investigation were statistically correlated with the occurrence of fractures (adjusted odds ratio: 4.8 and 3.6, respectively). Thus, these results emphasize that psychiatric symptoms are an essential risk factor for fracture in PD patients. (Received: September 4, 2012, Accepted: January 28, 2013)


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電子版ISSN 1344-8129 印刷版ISSN 1881-6096 医学書院

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