Kallmann症候群の1例

A CASE OF KALLMANN'S SYNDROME

　25歳，男性。二次性徴の欠如を主訴に受診。血中テストステロン，FSH低値。染色体46XY。LH-RHテスト，hCGテストではやや低反応を示した。睾丸生検は高度の造精機能障害を認めた。指極が身長を上回り，嗅覚異常を認めた。以上により，嗅覚異常を伴う低ゴナドトロピン性腺機能不全，つまりKallmann症候群と診断した。

A 25-year-old male was consulted to our hospital, complaining of lack of the secondary sexual characteristics. The basal levels of testosterone and follicle stimulating hormone (FSH) were low. His karyotype was 46, XY. The response of LH-RH test and hCG test were poor. Testicular biopsy revealed severe hypospermatogenesis. His arm span was larger than his stature. He was also found to have anosmia. This case, presenting a hypogonadotropic hypogonadism and anosmia, was considered to be consistent with Kallmann's syndrome.