グラビッツ腫瘍の皮膚転移例

SKIN METASTASIS OF HYPERNEPHROMA

はじめに

　グラビッツ腫瘍において転移を見ることは数多く，その経路は，血行性，淋巴行性および腎被膜・腎盂・尿管・下大静脈に直接浸潤する型が知られている。しかし皮膚に転移することは比較的稀とされている。最近著者はグラビッツ腫瘍の皮膚転移を示した1例を経験したのでここに報告し，本邦における昭和35年から昭和43年までの9年間の文献上に見られる本症の転移巣などにつき若干の統計的観察を行なつたので述べてみたい。

A 50-year-old man had received nephrectomy of the left kidny due to Grawitz's tumor. A hen-egg-sized tumor was found on the flexor aspect of cubital region about 5 years ago, which enlarged gradually. About 6 months ago many tumors with the same characteristics appeared over the entire body surface, and nodules were proved on the operation scar. The tumors were smooth, discrete, with normal skin color, walnut to egg in size, elastic soft or hard, and were 9 in number, with-out subjective symptoms. Roentgenogram revealed no abdormality in the chest and bones.

Histologic specimen from the subcutaneous tumor showed alveolar structure of tumor nests composed of large, atypical, pale cells in the deep layer of dermis and subcutis. In some parts they showed adenoid structure. The clear cells contained lipids.

Statistical studies on the reported cases of metastasis of hypernephroma in Japan from 1960 to 1966 were performed.