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GANGRENE OF THE FINGERS AND TOES IN SYSTEMIC LUPUS ERYTHEMATOSUS Kiyoshi NAKAYASU 1 , Junji IKADA 1 1Department of Dermatology, Kyoto Prefectural University of Medicine pp.831-836
Published Date 1969/8/1
DOI https://doi.org/10.11477/mf.1412200541
  • Abstract
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A 24-year-old housewife was first seen on Jan. 17, 1968. She had abortion three times in the past history She noticed itchy erythemas and papules on the trunk and extremities, and edematous butterfly-shaped erythema on the face with fever and arthralgia one month ago. She has been suffered from acrocyanosis with sever pain since 2 weeks, which followed acute gangrene of the left index, middle, ring and right index and small fingers and then all the right toes and tip of left first toe.

Accelerated sedimentation rate, increased γ-globulin level of the serum, negative STS, CRP (4+), ASL (250u), positive LE cell, moderate albuminuria, moderate microhematuria were proved. Stenosis was proved by arteriography of extremities.

Histologic specimen from the erythema of the face was typical LE. Specimen from the cyanotic area of the right index finger showed necrosis of epidermis and thromboangitis.

Adrenocortical hormone inhibited the progress of gangrene and diminished pain. Amputation of the sites of gangrene was performed.

Among the vascular disturbances of the skin in SLE gangrene of fingers and toes was very rare. Only 8 cases in Japan including the authors have been reported.


Copyright © 1969, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1324 印刷版ISSN 0021-4973 医学書院

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