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CRST SYNDROME Atsushi MUNAKATA 1 , Masaaki OGIU 1 , Shigeru TAKAGI 1 1Department of Dermatology, Nippon Medical School pp.303-308
Published Date 1969/3/1
DOI https://doi.org/10.11477/mf.1412200480
  • Abstract
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A 57-year-old woman has had Reynaud's phenomenon since about 40 years of age followed by sclerodactylia and telangiectasia on the forehead, cheeks and lips, and calcium deposition in the soft tissues of the extremities.

Laboratory tests revealed slight anemia, decreased grasping power, increased creatine and decreased creatinine level in the urine. Roentgenologic studies proved increased lung markings, decreased tonus of the esophagus and small intestines, especially cystic enlargement of the small intestines. These were characteristic changes of diffuse scleroderma and suggested that this syndrome was a kind of diffuse scleroderma. This syndrome is, therefore, nothing but scleroderma accompanied by four symptoms concurrently which have been known as associated changes of diffuse scleroderma. But it takes relatively benign, chronic course and it may be proper to understand and study as a syndrome.


Copyright © 1969, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1324 印刷版ISSN 0021-4973 医学書院

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