遺伝素因が疑われた完全型Melkersson-Rosenthal症候群の1例

Melkersson-Rosenthal Syndrome: Report of a Case

　はじめに

　Melkersson-Rosenthal症候群（以下MRS）は反復性顔面浮腫，再発性顔面神経麻痺，溝状舌を特徴とする比較的まれな症候群であり，なかでも3主徴が揃う完全型，また家族性発症を認める症例はともに例が少ない。今回われわれは3主徴ともに揃う完全型で，しかも家族性発症が疑われるMRS症例を経験したので報告する。

Melkersson-Rosenthal syndrome (MRS) is a rare syndrome consisting of a classical triad of recurrent facial palsy, facial swelling, and fissured tongue. A male patient presented with triad and had a family history of facial palsy. Our clinical diagnosis was typical MRS. Biopsies were taken from his lower lip. However, histology showed non-specific inflam-mation with no evidence of “cheilitis granu-lomatosa”. During his hospitalization facial nerve decompression operation was not performed, but he was treated by the Stennert's method. Two weeks later, his facial nerve function showed gradual improvement.