一過性黒内障を繰り返した抗リン脂質抗体症候群の2例

Recurrent amaurosis fugax in two cases of anti-phospholipid antibody syndrome

　一過性黒内障を繰り返した抗リン脂質抗体症候群の2例を経験した。症例1は全身性エリテマトーデスの患者で，他の神経症候なく，血管系にも病変はみられなかった。症例2は，一過性脳虚血発作の既往があり，経食道心エコーで心房中隔瘤がみられた。症例1はIupus anticoagulant陽性で，症例2は抗カルジオリピン抗体陽性だった。2症例の眼症状の発症に抗リン脂質抗体の関与が考えられた。一過性黒内障では，血管病変の検査に加えて抗リン脂質抗体も含めた凝固系の検査が必要である。

We observed recurrent amaurosis fugax in two females aged 46 and 78 years respectively. The former had been suffering from systemic lupus erythematosus since 25 years of age and were under systemic corticosteroid therapy. She was free of neurological or vascular disorders. The latter had a past history of transient ischemic cardiac attack. Transesophageal echocardiography led to the detection of atrial septal aneurysm. The former was positive for lupus anticoagulant and the latter was positive for anti-cardiolipin antibody. These findings show that anti-phospholipid antibodies might be involved in the recurrent amau-rosis fugax in the two cases.