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不明熱をacyclovirにて加療中のAIDS患者が,左眼にサイトメガロウイルス網膜炎を発症した。投与中のacyclovirとazidothymidineを継続したうえ,汎網膜光凝固術を施行した。左眼の網膜炎は増悪し3か月後に失明したが,網膜剥離の発症はなかった。さらに2か月後には右眼にも網膜炎を発症し,その3週間後に死亡した。サイトメガロウイルス網膜炎では末期には網膜剥離が起こるといわれているが,本例ではganciclovir投与をうけなかったにもかかわらず,網膜剥離の発症はなかった。汎網膜光凝固術と発症前より投与されていたazidothymidineとacyclovirが効果的だった可能性が考えられる。
A 41-year-old male presented with cytomegalo-virus (CMV) retinitis in his left eye. He had been diagnosed as acquired immune deficiency syndrome (AIDS) 5 months before. The affected eye was treated by panretinal photocoagulation with sys-temic acyclovir and azidothymidine. Due to relapse of retinitis 3 months later, the visual acuity was reduced to no light perception. No retinal detach-mant was present. Another 2 months later, CMV retinitis developed in his right eye. Death ensued 3 weeks later. Above findings seem to indicate that panretinal photocoagulation with systemic acy-clovir and azidothymidine would prevent retinal detachment in CMV retinitis.
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