視神経疾患診断における短潜時視覚誘発反応（SVEP）の有用性の検討

Clinical usefulness of short latency visual evoked potentials in the diagnosis of optic nerve disorders

　視神経疾患46例65眼（視神経萎縮24例39眼，視神経炎13例16眼，外傷性視神経損傷9例10眼）に対して，短潜時視覚誘発反応（SVEP）を施行し，その有用性を検討した。63眼，95.4％にSVEP早期成分（N26・N32・N40）の消失を認めた。多発性硬化症の視神経炎例におけるパターン反転刺激視覚誘発反応（PVEP）の異常率と大差はなく，SVEPは視神経疾患，特にPVEPで評価しにくい低視力者，中心暗点例，固視不安定例，中間透光体混濁例に対し，有用な検査診断法と考えられた。

We examined 42 cases, 65 eyes, with optic nervediseases by means of short latency visual evokedpotential (SVEP) studies. The series included 24cases with optic atrophy (39 eyes), 13 optic neuritis(16 eyes) and 9 optic nerve injury (10 eyes). In 95%of 65 eyes in the series, we observed disappearanceof early components (N26, N32, N40) of SVEPwhich are known to reflect visual pathway poten-tials.

This incidence was almost the same as that ofpattern VEP abnormality in cases of optic neuritisdue to multiple sclerosis. SVEP was thus useful inthe detection of optic nerve disorders, particularlyin cases with low visual acuity, central scotoma,unstable fixation, or opacity of the media in whompattern VEP cannot be applied.