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Clinical features of malignant retinochoroidal lymphoma Jiro Seguchi 1 , Nobuhiko Matsuo 1 , Tetsuro Koyama 1 , Fumiko Masaoka 1 , Yoshinobu Fujiwara 1 , Tadashi Nakayama 2 1Dept of Ophthalmol, Okayama Univ Med Sch 2Dept of Ophthalmol, Okayama Red Cross Hosp pp.1313-1319
Published Date 1986/12/15
DOI https://doi.org/10.11477/mf.1410209905
  • Abstract
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We observed 4 patients with malignant lymphoma of the retina and the choroid during a 4-year period through 1984. The condition was bilateral in 3 cases and unilateral in 1. None of the patients manifested evi-dences of systemic malignant lymphoma when they sought medical advice for their eye conditions.

They manifested, as characteristic ophthalmological features, massive vitreous opacity, mild iridocyclitis and infiltrative retinal lesions. These eye lesions were sensitive to radiation and laser treatments, but not to topical or systemic corticosteroid.

The uveitis tended to recur after appearances of involvement of the central nervous system and other systemic organs. Death resulted in 3 patients, 5 to 42 months after their first visit to us. One affected eye could be examined pathologically post mortem. Malignant lymphoma cells infiltrated into the retina, the choroid, and the space between the retinal pigment epithelium and the Bruch's membrane. From our clinical observations, it seems that malig-nant lymphoma may arise as a primary lesion in the eye. Its course of ocular involvement can be divided into three phases : acute phase, phase of disappearance, and phase of reappearance and extraocular dissemination.

Rinsho Ganka (Jpn J Clin Ophthalmol) 40(12) : 1313-1319, 1986


Copyright © 1986, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-1308 印刷版ISSN 0370-5579 医学書院

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