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要約 背景:日本での原発性眼窩腫瘍と腫瘍性病変は,欧米よりもリンパ球増殖と炎症性病変が多いとされている。目的:原発性眼窩腫瘍と腫瘍性病変の自検例の報告である。対象と方法:過去6年間に当科を受診した原発性眼窩腫瘍と腫瘍性病変265例を診療録の記載に基づいて解析した。結果:男性119例,女性146例で,悪性腫瘍88例(33%),良性腫瘍177例(67%)であった。男性では悪性腫瘍45例(37%),良性腫瘍74例(63%)であり,女性では悪性腫瘍43例(29%),良性腫瘍103例(71%)であった。リンパ球増殖性病変85例(32%),炎症性病変59例(22%),血管性病変48例(18%),視神経腫瘍5例(2%),その他68例(26%)であった。以上の結果を国内2施設と欧米2施設からの報告と比較すると,日本では欧米よりもリンパ球増殖性病変の頻度が有意に高く,血管性病変と視神経腫瘍が有意に低かった(p<0.01)。結論:眼窩腫瘍と腫瘍性病変の内訳は,日本では欧米よりもリンパ球増殖性病変が多く,視神経腫瘍と血管性病変が少ないと考えられる。
Abstract. Background:Reportedly, lymphoid hyperplasia and inflammatory lesions are more frequent in Japan than in North America among orbital tumors and tumorous lesions. Purpose:To review primary orbital tumor and tumorous lesions seen by us. Cases:This retrospective study was made on 265 cases who were diagnosed with orbital tumor or tumorous lesion during the past 6 years. Results:Malignant tumor was present in 88 cases(33%) and benign tumor in 177 cases(67%). Among 119 males, malignant tumor was present in 45 cases(37%) and benign tumor in 74 cases(63%). Among 146 females, malignant tumor was present in 43 cases(29%) and benign tumor in 103 cases(71%). Lymphoplastic lesion was diagnosed in 85 cases(32%), followed by inflammatory lesion in 59 cases(22%), vascular lesion in 48 cases(18%), optic nerve tumor in 5 cases(2%) and others in 68 cases(26%). When compared with similar reports from Japan and North America, incidence of lymphoplastic lesion was significantly higher in the Japanese, and that of vascular lesion and optic nerve tumor was significantly lower(p<0.01). Conclusion:Among orbital tumor and tumorous lesions, the Japanese appear to have higher incidence of lymphoplastic lesion and lower incidence of vascular lesion and optic nerve tumor.
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