雑誌文献を検索します。書籍を検索する際には「書籍検索」を選択してください。

Brain and Nerve No to Shinkei Volume 45, Issue 6 （June 1993）

Brain and Nerve 脳と神経 45巻6号（1993年6月発行）

Japanese English

Neurological CPC・6

下肢優位の右片麻痺と無言状態を呈した70歳男性 A 70-year-old Man with Right Hemiparesis and Mutism 大熊泰之 ¹ , 八田里美 ¹ , 窪田実 ³ , 河野浩章 ² , 水谷喜彦 ¹ , 白井俊一 ² , 佐藤猛 ¹ , 今井壽正 ¹ , 小出輝 ³ , 水野美邦 ¹ Yasuyuki Ohkuma ¹ , Satomi Hatta ¹ , Minoru Kubota ³ , Hiroaki Kohno ² , Yoshihiko Mizutani ¹ , Toshikazu Shirai ² , Takeshi Sato ¹ , Hisamasa Imai ¹ , Hikaru Koide ³ , Yoshikuni Mizuno ¹ ¹順天堂大学医学部脳神経内科 ²順天堂大学医学部第二病理 ³順天堂大学医学部腎臓内科 ¹Department of Neurology, Juntendo University School of Medicine ²Department of Nephrology, Juntendo University School of Medicine ³Department of Pathology, Juntendo University School of Medicine キーワード： monoparesis , mutism , aphasia , frontal lobe , supplementary motor cortex Keyword: monoparesis , mutism , aphasia , frontal lobe , supplementary motor cortex pp.579-584

発行日 1993年6月1日 Published Date 1993/6/1

DOI https://doi.org/10.11477/mf.1406900501

PDF(9398KB)

有料閲覧

Abstract 文献概要
1ページ目 Look Inside

症例提示

　症例　TM 70歳右利き男性（90-84551）。

　主訴　右片麻痺，言語障害。

We report a 70-year-old man who had a sudden onset of right hemiparesis and mutism. The lower extremity was more involved than the upper one.

He had a long history of diabetes and chronic renal failure for which hemodialysis was necessary. On August 30, 1990, he had an sudden onset of right hemiparesis and mutism. Neurological examination revealed awake but mute in no acute distress. He could only respond to very simple commands such as opening his mouth or protruding his tongue. He did not appear to understand more difficult ques-tions. In addition, he could not answer verbally. He was totally mute. Cranial nerves appeared intact except for slight right central facial paresis and severe diabetic retinopathy. He had complete paraly-sis of his right leg and a moderate weakness in his right upper extremity. Deep reflexes were dimini-shed in both upper extremities and absent in the lower limbs. Frotal signs such as grasp and snout reflexes were present.

Cranial CT scans revealed an ill-defined low density area in the left parasagittal subcortical area and a part of the anterior cerebral artery territory. The supplementary motor area appeared at least in part to be involved. He was treated with glycerol and other supportive cares, however, his clinical course was complicated by pneumonia, heart fail-ure, septicemia, and he expired two months after hisstroke.

The patient was dicussed in a neurological CPCand the chief discussant arrived at a conclusion that he had an artery-to-artery embolism at the internal carotid bifurcation resulting in the cerebral infarc-tion mainly in the territory of the anterior cerebral artery.

Post-mortem examination revealed an infarct involving the territory of the left anterior cerebral artery, but the artery itself was patent. The infarct was thought to be of embolic nature. The supple-mentary motor cortex and its adjacent subcortical area was also involved.

This patient appeared important that his clinical feature, that is mutism and aphasia-like condition, appeared in all likelihood to be caused by a lesion in the dominant medial frontal lobe including the sup-plementary motor cortex and its efferent subcor-tical fibers.