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HISTOPATHOLOGICAL STUDIES OF THE SURAL NERVES IN THE DIABETIC PATIENTS Akio Ohnishi 1 1Department of Neurology, Neurological Institute, Faculty of Medicine Kyushu University pp.453-461
Published Date 1973/4/1
DOI https://doi.org/10.11477/mf.1406203306
  • Abstract
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The fascicular biopsy of the sural nerves in the 6 diabetic patients was performed. The pathology of the sural nerves was investigated light-and electronmicroscopically, and concluded as follows :

1) In the myelinated fibers findings of both Wallerian degeneration and segmental demyelina-tion were almost equally encountered. The Waller-ian degeneration is partly subsequent to the seg-mental demyelination, but it must be considered that the primary Wallerian degeneration could exist in the patients.

2) The number of the myelinated fibers per square millimeter was remarkably decreased in 3 cases and slightly in 2 cases among 6.

3) The onion bulb structure was observed in 3 cases light-microscopically and in 4 cases electron-microscopically among 6 cases.

4) Degeneration of both unmyelinated fibers and Schwann cells was prominent in 4 cases among 6. It was observed at the almost same frequency as the degeneration of myelinated fibers. It is not specific, but it could be said that it has some significance in the pathology of the sural nerves in diabetic patients.


Copyright © 1973, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 2185-405X 印刷版ISSN 0006-8969 医学書院

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