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Brain and Nerve No to Shinkei Volume 58, Issue 9 （September 2006）

Brain and Nerve 脳と神経 58巻9号（2006年9月発行）

Japanese English

原著

日本語版NPI-DとNPI-Qの妥当性と信頼性の検討 Validity and Reliability of the Japanese Version of the Neuropsychiatric Inventory Caregiver Distress Scale （NPI-D） and the Neuropsychiatric Inventory Brief Questionnaire Form （NPI-Q）松本直美 ¹ , 池田学 ¹ , 福原竜治 ¹ , 兵頭隆幸 ¹ , 石川智久 ¹ , 森崇明 ¹ , 豊田泰孝 ¹ , 松本光央 ¹ , 足立浩祥 ² , 品川俊一郎 ³ , 鉾石和彦 ¹ , 田辺敬貴 ¹ , 博野信次 ⁴ Naomi Matsumoto ¹ , Manabu Ikeda ¹ , Ryuji Fukuhara ¹ , Takayuki Hyodo ¹ , Tomohisa Ishikawa ¹ , Takaaki Mori ¹ , Yasutaka Toyota ¹ , Teruhisa Matsumoto ¹ , Hiroyoshi Adachi ² , Shunichiro Shinagawa ³ , Kazuhiko Hokoishi ¹ , Hirotaka Tanabe ¹ , Nobutsugu Hirono ⁴ ¹愛媛大学大学院医学系研究科脳・神経病態制御医学講座　脳とこころの医学 ²大阪大学保健センター ³東京慈恵会医科大学精神医学講座 ⁴神戸学院大学人文学部人間心理学科 ¹Department of Neuropsychiatry, Neuroscience Ehime University Graduate School of Medicine ²Osaka University Health Care Center ³Department of Psychiatry, The Jikei University School of Medicine ⁴Faculty of Humanities and Science, Department of Human Psychology, Kobe Gakuin University キーワード： dementia , Neuropsychiatric Inventory , NPI-brief questionnaire form , NPI-caregiver distress scale Keyword: dementia , Neuropsychiatric Inventory , NPI-brief questionnaire form , NPI-caregiver distress scale pp.785-790

発行日 2006年9月1日 Published Date 2006/9/1

DOI https://doi.org/10.11477/mf.1406100397

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目的：Neuropsychiatric Inventory（NPI）に対応した介護負担尺度NPI-Caregiver Distress Scale（NPI-D）とNPIのアンケート版NPI-Brief Questionnaire Form（NPI-Q）を邦訳し妥当性と信頼性を検討した。方法：対象は認知症患者152名。対象者にMMSE，主介護者にNPI-Q，NPI，NPI-D，Zarit介護負担尺度（ZBI）を施行し，ZBI・MMSEとNPI-Dを比較しNPI-Dの妥当性を，NPI・NPI-DとNPI-Qを比較しNPI-Qの妥当性を検討した。30名に別の評価者がNPI-Dを再評価しNPI-Dの信頼性を，27名にNPI-Qを再施行しNPI-Qの信頼性を検討した。結果・結論：日本語版NPI-D，NPI-Qは原著版とほぼ同等の妥当性と信頼性を有し，認知症患者の精神症状と介護者の負担度の評価に有用である。

Objective : Neuropsychiatric disturbances are common and burdensome symptoms of dementia. Assessment and measurement of neuropsychiatric disturbances are indispensable to the management of patients with dementia. Neuropsychiatric Inventory （NPI） is a comprehensive assessment tool that evaluates psychiatric symptoms in dementia. We translated the NPI-Caregiver Distress Scale part of NPI （NPI-D） and NPI-Brief Questionnaire Form （NPI-Q） into Japanese and examined their validity and reliability. Subjects and Methods : The subjects were 152 demented patients and the caregivers who lived with them. These patients consisted of 76 women and 76 men ; their mean age was 73.9 ±7.8 （S.D. ; range : 49 to 93） years. Their caregivers consisted of 46 men and 106 women ; their mean age was 65.0±11.4 （S.D. ; range : 35 to 90） years. The Mini-Mental State Examination （MMSE） was conducted with all patients and NPI-Q, NPI, NPI-D, and the Zarit caregiver burden interview （ZBI） were conducted with all caregivers. We examined validity of NPI-D by comparing its score with the MMSE and ZBI scores, and the validity of NPI-Q by comparing its score with the NPI and NPI-D scores. In order to evaluate test-retest reliability, NPI-D was re-adopted to 30 randomly selected caregivers by a different examiner one month later and NPI-Q was re-executed by 27 randomly selected caregivers one day later.

Results : Total NPI-D score was significantly correlated with ZBI （rs＝0.59, p＜0.01）. Test-retest reliability of NPI-D was adequate （ri＝0.47, p＜0.01）. Total NPI-Q severity score and distress score were strongly correlated with NPI （r＝0.77, p＜0.01） and NPI-D （r＝0.80, p＜0.01） scores, respectively. Test-retest reliability of the scores of NPI-Q was acceptably high （the severity score ; ri＝0.81, p＜0.01, the distress score ; ri＝0.80, p＜0.01）. Conclusion : The Japanese version of NPI-D and NPI-Q demonstrated sufficient validity and reliability as well as the original version of them. These are useful tools for evaluating psychiatric symptoms in demented patients and their caregivers' distress attributable to these symptoms.