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Hyperbaric Oxygen (HBO) Therapy Was Effective in A Case with CO Poisoning with An Interval of Two and A Half Months after the Accident Akihiko NEBU 1 , Manabu IKEDA 1 , Naruhiko MAKI 1 , Kazuhiko HOKOISHI 1 , Kenjiro KOMORI 1 , Hirotaka TANABE 1 1Department of Neuropsychiatry, Ehime University, School of Medicine Keyword: Carbon monoxide poisoning , Hyperbaric oxygen therapy , Neuropsychological tests , SPECT pp.1275-1281
Published Date 1998/12/15
DOI https://doi.org/10.11477/mf.1405904665
  • Abstract
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 A-42-year-old woman with carbon monoxide (CO) poisoning was evaluated by neuropsychological testing, brain magnetic resonance imaging (MRI), and single-photon emission computed tomography (SPECT) with 99mTc-hexamethylpropyleneamine oxide (HMPAO) . At an interval of two and a half months after the accident, the patient showed loss of drive, attention, and concentration. The SPECT scans demonstrated cerebral hypoperfusion in the bilateral frontal and mediotemporal regions. After 20 administrations of hyperbaric oxygen (HBO), the patient recovered remarkably. Cerebral bloodflow increased in both the frontal and mediotemporal regions as clinical recovery progressed. HBO was effective in CO poisoning beyond the acute or subacute phase. Comprehensive neuropsychological testing combined with brain functional imaging seems useful to evaluate clinical improvement and effect of HBO in patients with CO poisoning.


Copyright © 1998, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-126X 印刷版ISSN 0488-1281 医学書院

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