統合失調症男性患者における舌圧および握力の年齢変化の検討

Age-Related Alterations in Tongue Pressure and in Handgrip Strength in Male Schizophrenic Patients

抄録

　嚥下障害のない40〜79歳の男性統合失調症患者(52例)と健常者(48例)について握力，舌圧と薬の1日服用量(CP換算量，BPD換算量，DAP換算量)について検討した。統合失調症患者の舌圧と握力はどの年代でも健常者と比較して有意差(p＜0.05)をもって低下していた。健常者では年齢と舌圧，年齢と握力および舌圧と握力に相関を認めたが，統合失調症患者では年齢と握力のみ弱い相関を認めた。統合失調症患者の舌圧や握力は1日服用量と相関はなかった。40歳台の統合失調症患者の舌圧平均は70歳台の健常者の舌圧平均より低下しており(p＜0.05)，窒息などの可能性を考慮すべき状態と考えられた。

　This study assessed tongue pressure, handgrip strength, and daily medical treatments(chlorpromazine(CP)equivalent dose, biperiden(BPD)equivalent dose, and diazepam(DAP)equivalent dose)in male schizophrenic patients without dysphagia(52 cases；aged 40-79 years)and in healthy controls(48 cases；aged 40-79 years). It was determined that handgrip strength and tongue pressure in schizophrenic patients were lower than that in healthy controls among all ages(p＜0.05). Tongue pressure and handgrip strength correlated with age and with each other in healthy controls. The patients with schizophrenia exhibited only a weak correlation between handgrip strength and these parameters. Furthermore, tongue pressure and handgrip strength in patients with schizophrenia showed negligible correlations among the various daily medical treatments, including CP equivalent dose, BPD equivalent dose, and DAP equivalent dose. The maximum tongue pressure in 40-year-old schizophrenic patients was lower than that in healthy 70-year-olds(p＜0.05). These results suggest that 40-year-old schizophrenic patients already have a high risk of choking.