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Efficacy of Aripiprazole in a Child with Childhood Disintegrative Disorder Kazuya ONO 1 , Sakiko AZUSAWA 1 , Hirohito AOKI 1 , Asami ETOH 1 , Mina YUZAWA 1 , Ryota SUGIHARA 1 , Yuichi SUZUKI 1 , Ayumi YAMAO 1 , Eri OSAKU 1 , Hikaru SETO 1 , Shinji OKINO 1 , Koji NAKAMURA 1 , Kazuhiko NAKAYAMA 1 1Department Psychiatry Tokyo Jikei Univercity School of Medicine, Tokyo, Japan Keyword: Child disintegrated disorders , Autistic spectrum disorders , Conversion disorder , Regression , Aripiprazole pp.211-218
Published Date 2015/3/15
DOI https://doi.org/10.11477/mf.1405204875
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 We are presenting a case of a 14-year-old female child who presented with normal development until 10 years of age, followed by deterioration in previously acquired language skills and leg movements, suggestive of childhood disintegrative disorder. After the onset, significant regression in language gradually appeared, followed by significant reduction in communication skills and stereotypical repetitive violent face slapping. Subsequently, we administered two types of serotonin reuptake inhibitors, but there was no significant effect. Finally, after increasing the aripiprazole to 24mg, the patient experienced a significant improvement. We are reporting on this case becourse this paient's condition is very rare, and this is the first report on the efficacy of aripiprazole in a child with childhood disintegrative disorder.


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電子版ISSN 1882-126X 印刷版ISSN 0488-1281 医学書院

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