Japanese
English
- 有料閲覧
- Abstract 文献概要
- 1ページ目 Look Inside
抄録 側頭葉てんかん患者にみられる開瞼時眼球運動の特徴を発作波焦点側との関連性から検討することを目的とし,側頭葉てんかん患者46名を対象として,発作間歇期の脳波を用いて発作波の焦点部位別に3群に分け,開瞼時眼球運動の検査を行った。また,その結果を慢性分裂病患者50名,正常対照者50名の結果と比較した。右側焦点群では正常群とほぼ同等の結果が得られたのに対して,左側焦点群では,右側焦点群と比べて明らかに異なり,分裂病群の値により近い結果が得られた。このことから,側頭葉てんかん患者において,発作波焦点側によって視覚的行動に相違がみられることが示唆された。またこの結果は,分裂病様の精神症状を示す側頭葉てんかんの症例は,脳波上,左側頭部に発作波焦点を持つものが多いという従来の知見と精神生理学的に関連するものであると考えられた。最後に眼球運動と抗てんかん薬との関係についても考察を加えた。
In our previous studies we reported that chronic schizophrenic patients had less frequent eye movements and a more limited area of inspection than normal subjects. This study was conducted to clarify the differences in eye movements of patients with temporal lobe epilepsy (TLE) in comparison with schizophrenics or normal controls.
Forty-six patients with TLE, 50 chronic schizophrenics and 50 normal controls were examined. The 46 epileptics consisted of 21 "left"-sided patients, 12 "right"-sided patients and 13 "bilateral" patients, classified according to the laterality of temporal spike foci in interictal electroencephalograms. While each subject viewed the "S" -shaped figure for 15 seconds, the eye movements and fixation points were recorded on an eye-mark recorder. The recorded data were analyzed with a computerized system.
As a result, there were similarities and differences between the eye movements of patients with TLE according to the laterality of temporal spike foci: The "left" group showed mostly different results from the "right" group. There were some similarities between the "left" group and schizophrenics. The "right" group showed mostly similar results to the normal controls.
Flor-Henry and others have reported that left-sided temporal lobe lesions in particular were associated with schizophreniform symptoms. The results of this study on eye movements of the patients with TLE might give support to their findings, although in this study most of the epileptics had no schizophreniform symptoms.
Copyright © 1989, Igaku-Shoin Ltd. All rights reserved.