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 Our report is concerned with 6 cases of Marihuana psychosis due to long-term Marihuana use.

 The onset of psychosis in all cases was associated with massive abuse of Marihuana or high cconcentration of THC in the blood.

 It was obvious that the outbreak of psychosis was associated with the psychological factors underlying the lifestyles of the subjects. Their clinical pictures were characterized by toxic psychosis, and, in all cases, amotivational syndrome and hallucinatory paranoid state were recognized.

 In addition to these syndromes, the histories of the subjects showed combinations of pathological states such as change of mood and drive instinct, impulsive action and flight, and lack of concentration, etc.

 The psychosis continued for 1~3 months from the initiation of therapy. However, fluctuation or even flash-back, occurred during improvement of these syndromes.

 Though positive syndrome subsided, amotivational syndrome was remained constantly, and, in some cases, it never disappeared completely.

 Our results suggested the possibility that progressional psychosis transferred into chronic personality disorder in some environmental and clinical circumstances.

Copyright © 1989, Igaku-Shoin Ltd. All rights reserved.


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