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A Case of Psychotic State of a Boy with Wegener's Granulomatosis Hiroyuki Makihara 1 , Sumako Etani 2 1Department or Neuropsychiatry, Hyogo College of Medicille 2Department of Pediatrics, Hyogo College of Medicine Keyword: Symptomatic psychosis , Wegener's granulomatosis , Collagen disease , Psychosis in systemic lupus erythcmatosus pp.535-540
Published Date 1983/5/15
DOI https://doi.org/10.11477/mf.1405203589
  • Abstract
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 Psychiatric disturbances in systemic lupus erythematosus are well known, and also in other collagen diseases as sclerodermia, periarteritis nodosa, and dermatomyositis, psychiatric symptoms are seen in the literature. The authors reported a fourteen-year-old boy of Wegener's granulomatosis who developed an acute psychotic episode with very slight cloudiness of consciousness and recovered from it gradually through the stage of slow mental activities. Among his acute mental symptoms were visual and auditory hallucinations, disturbance of thought, excitation, insomnia, and others.

 Schizophrenia, brain organic psychosis, and steroids-induced psychosis were discussed and excluded. This case was diagnosed as a psychotic state which was produced by Wegener's granulomatosis.

 Clinical features and course of psychiatric symptoms of the case were compared with those seen in two children of systemic lupus erythematosus which the authors had reported.

 Discussing the authors' cases and the literature, it was assumed that the pathogenesis of psychotic state in collagen diseases contains not only such brain organic damages as vascular lesions in central nervous system, but also metabolic-toxic process affecting functioning of the brain.


Copyright © 1983, Igaku-Shoin Ltd. All rights reserved.

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電子版ISSN 1882-126X 印刷版ISSN 0488-1281 医学書院

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