Seishin Igaku Volume 54, Issue 12 (December 2012)

Deterioration of Stereotypies in a Patient with Semantic Dementia Miwako IZUMI 1 , Kenjiro KOMORI 2 , Takeshi IKEUCHI 3 , Kou TANAKA 4 , Masaharu TANAKA 4 , Toru IMAMURA 5 , Manabu IKEDA 6 1Psychology Unit, Mishima Hospital, Nagaoka, Japan 2Clinical Psychology Unit, Zaidan Niihama Hospital 3Department of Neurology, Niigata University 4Department of Psychiatry, Mishima Hospital 5Field of Speech, Language and Hearing Sciences, Graduate School of Health Sciences, Niigata University of Health and Welfare 6Department of Neuropsychiatry, Faculty of Life Sciences, Kumamoto University Keyword: Stereotypy , Fronto-temporal lobar degeneration , Semantic dementia , Basal ganglia-thalamo-cortical circuits pp.1191-1199
Published Date 2012/12/15
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 We report the case of a 72-year-old right-handed woman who showed various stereotypies as semantic dementia progressed. At initial assessment, MRI showed focal atrophies in the anterior temporal lobes, which were more severe in the left lobe. She exhibited complicated stereotypies such as wearing clothes of the same color or using the same phrases. At a three-year follow-up, MRI showed increasing atrophy in the caudate nucleus and frontal lobes in addition to that in the temporal lobes, at the same time, she displayed simpler stereotypies for example, clapping, chewing, and ‘palilalia'. These findings suggest that the simplification of the stereotypies observed in this case was associated with basal ganglia-thalamo-cortical circuit dysfunction.

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54巻12号 (2012年12月)
電子版ISSN 1882-126X 印刷版ISSN 0488-1281 医学書院